One such chemical modification is cytidine acetylation (N4-acetylcytidine). Until now, the precise function of this chemical modification within cells has not been clearly understood. In particular, ...

CRISPR-Cas13, a powerful RNA-targeting technology is gaining increasing attention as a next-generation gene therapy platform due to its precision and reduced side effects. Utilizing this system, ...

A chemical modification in the HIV-1 RNA genome whose function has been a matter of scientific debate is now confirmed to be key to the virus's ability to survive and thrive after infecting host cells ...

< Photo 1. (From left) Professor Won Do Heo and Jihwan Yu, a Ph.D. Candidate of the Department of Biological Sciences > CRISPR-Cas13, a powerful RNA-targeting technology is gaining increasing ...

Researchers at the Ohio State University report they have settled a matter of scientific debate. In a new study, the researchers discovered a chemical modification in the HIV-1 RNA genome that is now ...

RNA molecules are an integral part of the human body: In cells, they ensure the transfer of genetic information and regulate the activity of genes. Some even act as catalysts, allowing chemical ...

Suggested Citation: "2 Importance and Impacts of RNA Modifications in Biology, Disease, Medicine, and Society." National Academies of Sciences, Engineering, and Medicine. 2024. Charting a Future for ...

A Northwestern Medicine study published in the Journal of Clinical Investigation has uncovered a connection between a well-known cancer-related protein and a major RNA modification process, which may ...

The hematopoietic system is a complex tissue characterized by multiple layers of stem cells, progenitor cells, and mature blood cells. Operating under normal conditions, it ensures a continuous and ...

About 95 % of human genes can produce different RNAs through a process called 'alternative splicing'. If you have ever read about cells, genes or DNA, you must have heard about RNA also. Chemically, ...