Single cell gene expression studies often rely on single-cell RNA sequencing (scRNA-seq) alone. While scRNA-seq reveals which genes are turned on, it does not capture protein expression or changes to ...

Single-cell transcriptomics has revolutionised our understanding of the cellular complexity underlying neurodegenerative disorders by enabling the high-resolution profiling of individual brain cells.

Initially, cells are dissociated from liver tissues into single-cell suspensions using in vivo enzymatic perfusion or ex vivo digestion methods. The cells of interest are then enriched from the ...

A wave of spatial transcriptomics studies has produced gene-expression atlases that span entire organs and whole organisms, from mouse embryos to the roundworm C. elegans to 31 human tissues. These ...

A research team at the Max Planck Institute for Chemical Ecology has successfully combined single-cell RNA sequencing (scRNA-seq) and single-cell mass spectrometry (scMS) analysis on the same plant ...

A new study constructs the first 3D single-cell brain atlas of the lamprey, uncovering the 450-million-year-old molecular blueprint of vertebrates.

The single-cell genomics industry does not stop advancing, with a steady stream of new companies, kits, acquisitions, and more. One new company, ArgenTag, was founded in Argentina during the COVID-19 ...

A new study led by researchers at UTHealth Houston investigated both gene expression and regulation at single cell levels to reveal disruptions in gene function in three brain regions of patients with ...

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